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Structural Genomics: Exploring the 3D Protein Landscape

How increased coverage of the structure space is transforming the field of biology

When the human genome was completely sequenced in 2003, researchers were already pondering how biomedicine could make use of it.  One hope was that the sequences would lead to a greater...
Jan, 01, 2010
FOLLOW THE MONEY: Big Grants in Biomedical Computing

Several big-dollar initiatives received NIH funding in late 2010

In the current economic climate, every research dollar counts. Fortunately, when it comes to biomedical computing, not everyone has been left counting change. Several big-dollar initiatives received...
brain, immunity, network
Apr, 01, 2011
Biology: A Game for a Crowd

Crowdsourced games and competitions fill an important niche

The rules of Phylo are simple: drag colored blocks across rows on the computer screen until similar colors line up. Within minutes of launching the game, any average person can learn how to play and...
Mar, 01, 2014
Top 12 List for Biocomputing: A Decade of Progress and Challenges Ahead

Looking back, and looking forward.

Editor’s Note: In addition to asking 10 experts to weigh in on Eric Jakobsson’s 2005 Top Ten Challenges for the field of biomedical computing (Top Ten Retrospective, in this issue),...
Jun, 18, 2014
Network Biology: Converging on Answers to Complex Diseases

Network biology is allowing scientists to convert their cellular parts lists into insights about complex diseases

To parents, the symptoms of autism can seem to appear from out of the blue during a child's first few years of life. But in recent years, researchers have shown that genes involved in the...
Nov, 17, 2017
NewsBytes: Winter 2005-2006
T-Rex in the Slow Lane by Kristen Cobb   Tyrannosaurus rex is often pictured baring its teeth, crouching, and running swiftly after its prey, but these images are largely based on human fancy...
Jan, 01, 2006
On Simulating Growth and Form

Simulations can teach us how young bodies and faces develop; how an artery compensates for decades of fatty plaque deposits by growing and thickening its walls; how tissue engineers can best coax endothelial cells to develop into organized sheets of skin for burn patients; and how cancerous tumors invade neighboring tissue.

For better or for worse, and on many levels, our tissues never stop growing and changing. While developing from childhood to old age, we grow not only bone, cartilage, fat, muscle and skin, but also...
Apr, 01, 2008
A Tipping Point for Function Prediction
There comes a tipping point in systems-biology studies of gene function where knowing some genes’ functions can, using a computational approach, help hone in on the functions of other genes....
Apr, 01, 2010
Biological Evidence for Turing Patterns

Mouse hair development patterns follow Turing's predictions

In the 1950s, computer science pioneer Alan Turing suggested an elegantly simple mechanism for how biological patterns such as scales, feathers, and hair might form. Now, more than fifty years later...
Apr, 01, 2007
Point/Counterpoint: Should there be a separate funding mechanism for the development and maintenance of software and infrastructure?
  POINT/   NO:  Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications. Biomedicine has a strong...
Jul, 01, 2009
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