Central repository of information on genes and proteins requires participation by the scientific community
Model fits experimental evidence
Experts reflect on challenges identified ten years ago.
Computing using time steps -- a necessary approximation
Modelers are using recent gains in computational power to consider the complex interactions of hundreds or thousands of macromolecules at once--a necessary first step toward whole cell simulation
To understand biology—and provide appropriate medical care—scientists need to understand interactions across multiple scales. Hence the Physiome.
Building upon the clues provided by GWAS to gain new insights
Computational modeling can help fill gaps in how we develop and review new drugs and devices
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