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Dogs, Doses, and Devices: The FDA's Ambitious Plans for Computational Modeling

Computational modeling can help fill gaps in how we develop and review new drugs and devices

What role does computational modeling play at the United States Food and Drug Administration (FDA)?  If you ask Paul Watkins, MD, director of the Hamner—University of North Carolina...
devices, drug discovery, FDA, modeling
Aug, 31, 2011
Making DNA Smile

Researcher coaxes long strands of DNA into predetermined geometric shapes

Designing nanostructures of DNA just got easier. Paul Rothemund, PhD, a senior research fellow at Caltech has found a way to coax a long strand of DNA into a predetermined geometric shape by mixing...
Jun, 30, 2006
Smart Embedded Devices: Here They Come

Machine learning for an artificial pancreas and deep brain stimulation

Embedded medical devices that both detect symptoms and treat them have existed for decades. Take, for example, the heart pacemaker. But a new generation of implants could soon emerge to do something...
diabetes, epilepsy, machine learning, pancreas, Parkinsons
Oct, 19, 2012
Mobile Health: BD2K Centers Harness Sensor Data

How mobile technology and data science are poised to revolutionize healthcare--with BD2K Centers paving the way

Relevant NIH Institutes: NIMH, NINDS, NHLBI, NIA, NIBIB, NIDA, NHGRI, NICHD, and NIAAA   Having already revolutionized fields ranging from communications to finance, mobile technology and data...
Jun, 14, 2017
Wearing Your Health on Your Sleeve

How big data from mobile apps and sensors may revolutionize healthcare

My phone buzzes. It’s Mood Matters, a mood-tracking app developed by the startup Ginger.io. “We notice you haven’t logged any recent physical activity,” it alerts me, linking...
Jun, 03, 2015
Wearable Technology: Making Health Addictive

Harnessing the power of our fascination with mobile devices

The hype around wearables is deafening. I say this from the perspective of someone who saw their application in chronic illness management more than 15 years ago. Of course, at that time, it was less...
Jun, 01, 2015
Doing the Heart Good: Translating Models to the Clinic

Cardiovascular models are moving to the bedside

Pacemakers, heart-lung machines, stents and artificial hearts all sprang from successful partnerships between engineers and doctors. “From its inception in the 1950s, heart surgery has...
cardiovascular, clinical, translation
Mar, 01, 2014
Introducing: The Mobilize Center

Bringing big data to gait analysis

In 1891, when researchers first analyzed the mechanics of walking in three dimensions, the process was painstaking and cumbersome. It took six to eight hours just to prepare the subject for data...
Jan, 07, 2015
Bridging the Scientific Divide: Enabling Sharing through Biomedical Computing

How to share knowledge, data, tools, and computational resources in a sustainable manner

Once upon a time, a deep divide existed between scientists who did and those who did not have easy access to scientific content (journals, lectures, data), hardware (imaging devices, lab instruments...
sharing
Mar, 31, 2011
Getting It Right: Better Validation Key to Progress in Biomedical Computing

Bringing models closer to reality

When the ill-fated space shuttle Columbia launched on January 16, 2003, a large piece of foam fell off and hit the left wing. Alerted of the impact, NASA engineers used a computer model to predict...
7009, competitions, outsource, self-assessment, validation
Oct, 19, 2012
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